Study of graft arteries – Study Design

• Introduction
• Background
• Study Design
• Data Collection
• Analysis
• Data
• Glossary

• Patient risk factors

  • Age in years
  • Sex
  • Presence of diabetes
  • History of cigarette smoking
  • Presence of peripheral vascular disease
  • Presence of cerebrovascular disease
  • Presence of hypercholesterolemia

• Arterial abnormalities (obtained from histopathology)

  (For details about the histopathology, see Background.)

  • Presence of intimal thickening
  • Presence of medial calcification or atherosclerosis
  • Type of atherosclerosis

• Indicators of disease severity (obtained from morphometric analysis)

  (For details about the morphometric analysis, see Background.)

  • Percentage of luminal narrowing
  • Intimal thickness index
  • Intima-to-media ratio

• Other measures obtained from morphometric analysis

  • Diameter of lumen + intima
  • Internal elastic lamina area
  • Intimal area
  • Medial area
  • Width of intima
  • Width of media

Statistician’s description of study design

Brian and Lek’s study used a clinical sample and made several measurements on two artery types for the same patients.