Study of graft arteries – Analysis

• Introduction
• Background
• Study Design
• Data Collection
• Analysis
• Data
• Glossary

Summary

Brian, Lek and their colleagues found that there were more abnormalities in radial arteries (RA) than in internal thoracic arteries (ITA). They also found differences between the arteries for a number of characteristics measured in morphometric analysis. They cautioned that care should be taken in using the radial artery for CABG surgery in some clinical subpopulations.

This figures shows estimates and 95% confidence intervals for the mean difference (RA – ITA) for three indices of severity of arterial disease:

Questions to consider

• Produce a summary table to describe the characteristics of the study participants.
• Produce visual displays to describe the results of the morphometric analysis of ITAs and RAs.
• Describe the distribution of each of the three main indices of severity of disease (%LN, ITI, IMR) using appropriate visual displays.
• Compare ITAs and RAs on the three main indices of severity of disease. Summarise your results with a confidence interval.
• Compare ITAs and RAs on the width and area measures obtained from the morphometric analyses. Calculate and plot confidence intervals to summarise your results.
• Which risk factors predict each of the three main indices of severity of disease? Conduct separate analyses for ITAs and RAs.
• Which risk factors predict the arterial abormalities identified by the pathologist? Examine one of the abnormalities and conduct separate analyses for ITAs and RAs.